Review on Research of Suppression Male Fertility and Male Contraceptive Drug Development by Natural Products
نویسندگان
چکیده
منابع مشابه
A Review on Male Fertility
Spermatogenesis is a complex process that involves stem-cell renewal, genome reorganization and genome repackaging, and that culminates in the production of motile gametes. Problems at all stages of spermatogenesis contribute to human infertility. Male infertility, is characterized by hypogonadism, decreased semen quality or ejaculatory dysfunction, accounts for approximately 20% of infertility...
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Knockout mice lacking the P2X(1) receptor appear normal, but fail to breed. Analysis of these mutant mice clearly shows that purinergic co-transmission has a physiological role in the was deferens. These findings also raise the possibility of developing non-hormonal ways of regulating male fertility.
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In recent years, male fertility has changed due to the effects of environmental, health and lifestyle factors and the infertility rate has increased, to the extent that male fertility may be affected by extreme heat, exposure to pesticides, radiation, substances Changes in radioactivity, lifestyle, stress and occupation. In the environment, there are ionizing and non-ionizing rays whose effect...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2013
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1300800840